Introduction:
Growth STimulation expressed gene 2 is a member of the interleukin-1 receptor family.
ST2 is listed as a class II indication for the prognosis of heart failure (HF). Soluble ST2 protein (sST2) is a biomarker of vascular health, which has diagnostic and prognostic value for various cardiovascular diseases, including coronary artery disease, myocardial infarction, atherosclerosis, giant cell arteritis, and acute aortic dissection , Ischemic stroke, obesity and diabetes. Myocardial hypertrophy, fibrosis and ventricular dysfunction are related to abnormal levels of sST2.
Advantage:
Simple operation and fast response (15min)
Clinical significance:
Higher concentration of soluble ST2 is associated with increased myocardial fibrosis, adverse cardiac remodeling, and worse cardiovascular outcomes.
Intended use:
ICU, Respiratory Medicine, Emergency department, Cardiology, emergency car