Intended Use:
The kit is used for in vitro quantitative detection of human leukocyte antigen B27 gene (including B2702, B2704, and B2705 subtypes) in human whole blood samples.
Ankylosing spondylitis (AS) is a rheumatic disease characterized by the involvement of the central axis and peripheral joints, and chronic inflammation and the formation of new bones. The disease is more common in adolescents. Severe joint dysfunction can occur within 10 years of onset. When the spine, sacroiliac joints and hip joints develop lesions, the lesions are irreversible. Among them, human leukocyte antigen-B27 (HLA-B27) is considered to have a strong correlation with AS, that is, the positive rate of HLA-B27 in AS patients is as high as 90%. The kit developed by our company can detect the B2702, B2704, and B2705 subtypes related to AS, but it cannot distinguish between different genotypes. The test results of this kit are for the auxiliary diagnosis of AS. The test results shall not be used as the only indicator of the patient's condition evaluation. The patient's clinical manifestations and other testing methods must be combined to make a comprehensive analysis of the condition.
Product order info:
Product Name: Human Leukocyte Antigen B27 Nucleic Acid Detection Kit (Fluorescence PCR Method)
Cat. No.: P118H
Specification : 32T/kit(non-prefilled)
Specimen: human whole blood samples.
Storage & Validity: -25℃~-15℃ for 12 months
Applicable Equipment:
ABI7500 real time PCR systems, TL988-IV real time PCR system, Gentier 96E real time PCR system, Gentier 96R real time PCR system and Gentier 48E real time PCR system.