Enzyme reagent kit P130H

solutionfor PCRdiagnostic

The MTHFR gene encodes methylene tetrahydrofolate dehydrogenase, a rate-limiting enzyme that regulates the metabolism of folate and methionine. It plays an important role in folate metabolism, DNA methylation, and DNA synthesis. The most common polymorphism of the MTHFR gene is C677T, which locates in the catalytic domain of MTHFR, and its polymorphism leads to decreased enzyme activity and thermolability. Tianlong Human MTHFR (C677T) Gene Polymorphism Detection Kit is for in vitro qualitative detection of the MTHFR genotype at the 677 genetic locus using PCR melting curve method. The detection results are intended to provide an auxiliary diagnosis for high-risk groups with low activity of methylenetetrahydrofolate reductase.