Pharmacology assay kit P164

genetichomocysteinefolic acid

Methylenetetrahydrofolate reductase (MTHFR) and methionine synthase reductase (MTRR) are key enzymes in the methionine-folate metabolism system, involving in the regulation of folic acid metabolism and in maintaining normal homocysteine levels in the body. People carrying mutated MTHFR/MTRR genotypes may have disordered folic acid metabolism, which leads to increased risks of neonatal neural tube defects, Down syndrome, and cleft lip and palate. And such people need more folic acid supplements to achieve the desired effect. Tianlong Human MTHFR\MTRR Gene Polymorphism Detection Kit provides qualitative detection of the genetic polymorphisms at the MTHFR (c.1298) and MTRR(c.66) using PCR melting curve method.