Thalassemia assay kit βTHA-MMC

whole bloodfor PCR

Beta thalassemia (β-thalassemia) is a kind of monogenic inheritance hemopathy due to expression imbalance of peptide chain caused by β-globin gene mutation, mostly caused by β-globin gene point mutations. The commonly seen mutation sites are CD41-42, IVS-II-654, -28, CD71/72, etc. Intended Use This kit is used for in vitro qualitative detection of β-thalassemia related β-globin gene point mutations in human whole blood sample, which can detect the commonly seen 23 kinds of mutations of β-globin gene: CD17 (AAG>TAG), CD14-15 (+G), -90 (C>T), Initiation codon (ATG>AGG), 5’UTR+43 to +40 (-AAAC), -28 (A>G), -29 (A>G), -30 (T>C), -32 (C>A), -31 (A>C), CD26 (GAG>AAG), CD27/28 (+C), IVS-I- 1 (G>T), IVS-I-5 (G>C), CD30 (AGG>GGG), IVS-I- (-3) (C>T), CD41-42 (- TTCT), CD43 (GAG>TAG), CD37(TGG>TAG), CD71-72 (+A), IVS-II-654 (C>T), IVS-II-5 (G＞C) and IVS-II-2(-T). General Specification Sample Type: anti-coagulation whole blood Precision: CV <3% LoD: 0.2 ng/μL Packing Specifications 25 tests/kit - 48 tests/kit