Leica antigen reagents

... decreased staining intensity. Proprietary reagents from Leica Biosystems or TBS-based wash buffer and diluents are recommended. Disclaimer Akt (Phosphorylated) is recommended for the detection of specific antigens ...

... large cell lymphoma (ALCL) is usually composed of large pleomorphic cells which are reported to express CD30 antigen and epithelial membrane antigen (EMA). These tumor cells tend to occur in younger individuals ...

Antigen Background Alpha Fetoprotein (AFP) is an oncofetal antigen of 70 kD found in body fluids, which if detected in high concentrations has clinical implications. AFP is expressed in fetal liver ...

Antigen Background Alpha-methylacyl-CoA racemase (AMACR), also known as p504s, is a mitochondrial and peroxisomal enzyme that is involved in bile acid biosynthesis and beta-oxidation of branched-chain fatty acids. ...

Antigen Background Alpha-synuclein is a protein of 140 amino acids and a member of the synuclein family. It shares 61% sequence homology with beta-synuclein and is highly conserved between vertebrate species. It does ...

Antigen Background Androgen receptor is a member of the superfamily of ligand responsive transcription regulators. The androgen receptor functions in the nucleus where it is believed to act as a transcriptional regulator ...

Antigen Background Bcl-2 is a member of a family of proteins that are involved in apoptosis. Bcl-2 is an integral inner mitochondrial membrane protein of 25 kD and has a wide tissue distribution. It is considered to ...

Antigen Background The catenins, (alpha, beta and gamma) are cytoplasmic proteins which bind to the highly conserved tail of the E-cadherin molecule. Beta-catenin is a component of the adherens junction, a multiprotein ...

Antigen Background Dystrophin associated glycoproteins (DAGs) are involved in the attachment of dystrophin to muscle membranes. The biological significance of this dystrophin/glycoprotein complex is not fully understood, ...

... acting as a functional ligand for the inducible adhesion molecule E-selectin. CA19-9 and CA50 (carcinoma associated mucin antigen) are useful serum markers in the diagnosis and follow up of gastrointestinal and pancreatic ...